The Cayce Historical Museum chronicles the history of the first European settlement in the South Carolina Midlands. The museum interprets the agricultural, social and cultural heritage of Old Saxe Gotha, Granby, Cayce and West Columbia areas. Exhibits emphasize periods of Colonial trade, agricultural development and transportation from the 18th Century to the present. Native American artifacts at the museum date back thousands of years to when they inhabited the land near the Broad, Saluda and Congaree Rivers.
The main building of the museum is a replica of a trading post which was built in the Cayce area in 1765. The trading post was seized by the British during the American Revolution and used as a fort.
The town of Cayce includes the site of Fort Granby, one of the earliest inland villages and the scene of two Revolutionary battles. The museum is open Tuesday through Friday from 9:00 a.m. until 4:00 p.m., and Saturday and Sunday from 2:00 p.m. until 5:00 p.m.